Bonnie Hunter of Quiltville does in her Pinapple Blossom quilt. I don't want to re-invent the wheel so I am just going to link to her website since she has some great photos on the technique.
I wanted to keep a bit of consistancy throughout the quilt but I ran out of both the tan and the brown fabrics. A trip to the LQS resulted in fabrics of the same color and value but a different shade. It works for me. *shrug* The only fabric that is consistant throughout the quilt turned out to be the blue/green stripe. I have recently re-discovered a love for stripes: a striped fabric makes something look more difficult than it really is, similar to knitting a pair of socks with self-striping yarn.
The inner 2" border was added of the tan/beige fabric to stop the eye and give it a place to rest from the busy center. A 3" border was added and then a 5" border. Do you know about Fibonacci sequence? I first learned of this from Caryl Bryer Fallert's website. It is a mathematic formula that results (at least in quilting) in a pleasing sequence. The number squence goes like this: 0, 1, 1, 2, 3, 5, 8, 13, and so on. Or 0+1=1, 1+1=2, 1+2=3, 2+3=5. This is where I got the width of my borders in relation to how much fabric I had on hand. *grin* To much information? It gets better. Think of pieces in a block similar to a log cabin: 1+1=2, etc, etc.
So there you have it. The sometimes haphazard design process that I use.